发明名称 |
GENE DELIVERY IN NANO SCALE MICELLE FORM CONTAINING ANTI-OXIDANT SUBSTANCES |
摘要 |
The present invention relates to a gene carrier in a nano micelle form containing anti-oxidants inside and a preparing method of the same. The present invention also relates to a gene transfer complex encountered with a nucleic acid material by mixing the gene carrier and the nucleic acid material. The gene transfer complex has a structure which contains the antioxidants in the interior of the micelle, reduces an oxidative stress induced when the nano sized gene complex flows into the inside of a cell, reduces damage to mitochondrial membrane, and improves gene transfer efficiency of the gene carrier. |
申请公布号 |
KR20140018454(A) |
申请公布日期 |
2014.02.13 |
申请号 |
KR20120079604 |
申请日期 |
2012.07.20 |
申请人 |
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY |
发明人 |
JEONG, JI HOON;LEE, MIN SANG |
分类号 |
A61K9/127;A61K31/375;A61K47/30 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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