发明名称 TOCOPHEROLS WITH REDUCED CONTENT OF PHENOLIC IMPURITIES
摘要 The present invention relates to a method of preparing a tocopherol or protected tocopherol with a reduced content of phenolic compound or protected phenolic compound, particularly of (2R,3R)-2,3,4,6,7-pentamethyl-2- (4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol or (2R,3R)-2,3,4,6,7- pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-yl acetate, comprising the step of contacting tocopherol or protected tocopherol in neat or in the form of a highly concentrated solution with an acid activated bleaching earth. This method is rather efficient in removal of substantial amounts of this impurity.
申请公布号 WO2014023846(A1) 申请公布日期 2014.02.13
申请号 WO2013EP66815 申请日期 2013.08.12
申请人 DSM IP ASSETS B.V. 发明人 WYSS, MARKUS
分类号 C07D311/72 主分类号 C07D311/72
代理机构 代理人
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