SYSTEM AND METHOD FOR IDENTIFYING COMPLEX PATTERNS OF AMINO ACIDS

摘要

SYSTEM AND METHOD FOR IDENTIFYING COMPLEX PATTERNS OF AMINO ACIDSA method and system are disclosed for identifying and/or locating complexpatterns in an amino acid sequence stored in a computer file or database.According to an aspect of the present invention, techniques are provided tofacilitate queries of protein databases. For protein descriptions receivedin response to the queries, embodiments of the present invention may scanthe received protein descriptions to identify and locate Replikin patterns.A Replikin pattern is defined to be a sequence of 7 to about 50 amino acidsthat include the following three (3) characteristics, each of which may berecognized by an embodiment of the present invention: (1) the sequence hasat least one lysine residue located six to ten amino acid residues from asecond lysine residue; (2) the sequence has at least one histidine residue;and (3) at least 6% of the amino acids in the sequence are lysine residues.[Figure 4]