| 发明名称 |
METHOD FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE |
| 摘要 |
Methods are provided for the synthesis of key intermediates for the synthesis of Argatroban monohydrate, ethyl (2R,4R)-1-[(2S)-2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methylpiperidine-2-carboxylate compounded with HCl. Such intermediates are also provided. |
| 申请公布号 |
EP2694493(A1) |
申请公布日期 |
2014.02.12 |
| 申请号 |
EP20120710293 |
申请日期 |
2012.03.26 |
| 申请人 |
LUNDBECK PHARMACEUTICALS ITALY S.P.A. |
发明人 |
STIVANELLO, MARIANO;HUBER, FLORIAN ANTON MARTIN;RICCI, ANTONIO |
| 分类号 |
C07D401/12;A61K31/4709 |
主分类号 |
C07D401/12 |
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