摘要 |
The invention generally provides processes and intermediate compounds useful for the production of (+)-opiates. Non-limiting examples of (+) opiates that may be derived from one or more compounds of the invention include (+)-noroxymorphone, (+)-naltrexone, (+)-naloxone, (+)-N-cyclopropylmethylnorhydrocodone, (+)-N-cycloproylmethylnorhydromorphone, (+)-N-allylnorhydrocodone, (+)-N-allylnorhydromorphone, (+)-noroxycodone, (+)-naltrexol, (+)-naloxol, and (+)-3-O-methyl-naltrexone. |
申请人 |
MALLINCKRODT LLC |
发明人 |
WANG, PETER, X.;JIANG, TAO;CANTRELL, GARY, L.;BERBERICH, DAVID, W.;TRAWICK, BOBBY, N.;OSIEK, TODD;LIAO, SUBO;MOSER, FRANK, W.;MCCLURG, JOSEPH, P. |