发明名称 |
MONOCLONAL ANTIBODIES AGAINST TISSUE FACTOR PATHWAY INHIBITOR (TFPI) |
摘要 |
Isolated monoclonal antibodies that bind to specific epitopes of human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. |
申请公布号 |
EP2694544(A2) |
申请公布日期 |
2014.02.12 |
申请号 |
EP20120762959 |
申请日期 |
2012.03.30 |
申请人 |
BAYER HEALTHCARE LLC |
发明人 |
WANG, ZHUOZHI;MURPHY, JOHN;MARQUARDT, TOBIAS;MOOSMAYER, DIETER |
分类号 |
C07K16/18;A61K39/395 |
主分类号 |
C07K16/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|