| 发明名称 |
CRYSTALLINE AND NON- CRYSTALLINE FORMS OF TOFACITINIB, AND A PHARMACEUTICAL COMPOSITION COMPRISING TOFACITINIB AND A PENETRATION ENHANCER |
| 摘要 |
The present invention discloses novel crystalline and non-crystalline forms of 3-((3R,4R)-4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-pip-eridin-1-yl)-3-oxopropionitrile, pharmaceutical composition containing the same, preparations thereof and the uses thereof. |
| 申请公布号 |
EP2694512(A1) |
申请公布日期 |
2014.02.12 |
| 申请号 |
EP20120715195 |
申请日期 |
2012.03.29 |
| 申请人 |
PFIZER INC. |
发明人 |
MURPHY, BRENDAN J.;WHITE, TIMOTHY D.;CHEKAL, BRIAN P.;JOHNSON, PHILLIP J.;FOTI, CHRISTOPHER JAMES;MARGULIS, LEONID A. |
| 分类号 |
C07D487/04;A61K31/519;A61P17/06 |
主分类号 |
C07D487/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
