发明名称 |
Method for detecting renal disease comprising measuring human megalin in urine |
摘要 |
The present invention relates to a detection kit and a detection marker used for diagnosing a renal disease. Also, the present invention relates to a method for diagnosing a renal disease using the megalin level in urine as an indicator for diagnosing a renal disorder in the form of a marker. In addition, the present invention relates to a method for evaluating effects of treating a renal disease. In particular, this invention provides a method for detecting a renal disease comprising measuring a human megalin ectodomain fragment existing in urine, wherein the large amount of human megalin ectodomain fragment excreted into the urine indicates the renal disorder. |
申请公布号 |
EP2696200(A1) |
申请公布日期 |
2014.02.12 |
申请号 |
EP20130191564 |
申请日期 |
2010.04.27 |
申请人 |
NIIGATA UNIVERSITY;JUNTENDO EDUCATIONAL FOUNDATION;DENKA SEIKEN CO., LTD. |
发明人 |
SAITO, AKIHIKO;TOMINO, YASUHIKO;ASANUMA, KATSUHIKO;OGASAWARA, SHINYA;KUROSAWA, HIROYUKI;HIRAYAMA, YOSHIAKI |
分类号 |
G01N33/53;C07K14/47;G01N33/543 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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