摘要 |
PURPOSE: A method for preparing novel benzofuran-2-carboxamide derivative is provided to prevent or treat MCH receptor-1 related diseases such as obesity, diabetes, metabolic disorder, anxiety, and depression. CONSTITUTION: A benzofuran-2-carboxamide derivative is denoted by chemical formula 1. A pharmaceuticalcomposition for preventing and treating MCH receptor-1 related diseases contains the derivative or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. A food composition for preventing or treating MCH receptor-1 related diseases contains the derivative or salt of hydrate thereof as an active ingredient. A method for preparing the derivative comprises a step of reacting a compound of chemical formula 2 with a compound of chemical formula 3 in a solvent. [Reference numerals] (AA) Condensation |