发明名称 |
ACETYLCHOLINESTERASE INHIBITORS FROM ACORN OF QUERCUS ACUTISSIMA |
摘要 |
PURPOSE: A method for preparing acetylcholine esterase inhibitor from arcon is provided to ensure simply obtain a large amount of gallic acid derivatives. CONSTITUTION: A method for preparing acetylcholine esterase inhibitor comprises: a step of pulverizing and freeze-drying acorn; a step of mixing 1 weight part of dry acorn and 80-120 weight parts of mixture solvent of spirit and water; a step of refluxing at 70-90°C for 3-5 hours; a step of mixing 1 weight part of the extract and 10-50 weight parts of distilled water to prepare mixture suspension; a step of adding 80-120 weight parts of first organic solvent and shaking for 20-60 minutes to remove water; a step of dissolving the concentrate in second organic solvent and removing insoluble material; and a step of extracting the materials of chemical formulas 1-3 using LH 20 column chromatography. The extract contains a material of chemical formulas 1-3. |
申请公布号 |
KR101359554(B1) |
申请公布日期 |
2014.02.11 |
申请号 |
KR20100108138 |
申请日期 |
2010.11.02 |
申请人 |
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发明人 |
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分类号 |
A61K31/05;A61K31/192;A61K36/185;A61P25/28 |
主分类号 |
A61K31/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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