发明名称 |
System and method of evaluation of stochastic interactions of a soluble ligand with a target cell population for optimization of drug design and delivery |
摘要 |
A computer system for recommending an optimal treatment protocol comprising a model of biological processes related to a disease. A treatment protocol generator generates a plurality of treatment protocols for treating a disease using drugs. A selector selects an optimal treatment protocol from the plurality of treatment protocols based on model. The model further comprises a pharmacokinetics macro module adapted to analyze interactions between a ligand and a population of target cells at a tissue level. The model further comprises a pharmacokinetics micro module adapted to analyze interactions between the ligand and a cell at an individual cell level. The pharmacokinetics micro module is adapted to model behavior of the ligand and receptors related to single cell level of ligand-cell interactions, as a stochastic process. |
申请公布号 |
US8650017(B2) |
申请公布日期 |
2014.02.11 |
申请号 |
US20060449648 |
申请日期 |
2006.06.09 |
申请人 |
KIRNASOVSKY OLEG U.;VAINSTEIN VLADIMIR;KOGAN YURI;AGUR ZVIA;OPTIMATA LTD. |
发明人 |
KIRNASOVSKY OLEG U.;VAINSTEIN VLADIMIR;KOGAN YURI;AGUR ZVIA |
分类号 |
G06G7/48;G01N31/00;G01N33/48;G06G7/58 |
主分类号 |
G06G7/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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