| 发明名称 |
INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 |
| 摘要 |
This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A2 enzymes (cPLA2), more particularly including inhibitors of cytosolic phospholipase A2 alpha enzymes (cPLA.alpha.). In some embodiments, the inhibitors have the Formula I: wherein the constituent variables are as defined herein. |
| 申请公布号 |
CA2607857(C) |
申请公布日期 |
2014.02.11 |
| 申请号 |
CA20062607857 |
申请日期 |
2006.05.26 |
| 申请人 |
WYETH |
发明人 |
MCKEW, JOHN C.;LEE, KATHERINE L.;CHEN, LIHREN;VARGAS, RICHARD;CLARK, JAMES D.;WILLIAMS, CARA;CLERIN, VALERIE;MARUSIC, SUZANA;PONG, KEVIN |
| 分类号 |
C07D209/14;A61K31/404;A61P11/00;A61P19/00;A61P25/00 |
主分类号 |
C07D209/14 |
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