发明名称 |
HETERODIMERIZED POLYPEPTIDE. |
摘要 |
<p>The present inventors produced a heterodimerized polypeptide having an Fc region that comprises two polypeptides having different amino acid sequences from each other (i.e., a first polypeptide and a second polypeptide), and thus succeeded in the production of a heterodimerized polypeptide containing an Fc region having an improved function compared with that of a homodimer having an Fc region composed only of the first polypeptide or a homodimer having an Fc region composed of the second polypeptide which are conventional techniques.</p> |
申请公布号 |
MX2013015366(A) |
申请公布日期 |
2014.02.11 |
申请号 |
MX20130015366 |
申请日期 |
2012.06.29 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
TOMOYUKI IGAWA;HIROTAKE SHIRAIWA;FUTA MIMOTO;TAICHI KURAMOCHI;SHOJIRO KADONO;HITOSHI KATADA;MEIRI KAWAZOE |
分类号 |
C12N15/09;A61K39/395;C07K16/28;C07K16/46 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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