| 发明名称 |
ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE |
| 摘要 |
The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kgamma. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. |
| 申请公布号 |
US2014038936(A1) |
申请公布日期 |
2014.02.06 |
| 申请号 |
US201313888960 |
申请日期 |
2013.05.07 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
ARONOV ALEX;COME JON H.;DAVIES ROBERT J.;PIERCE ALBERT CHARLES;COLLIER PHILIP N.;GREY RONALD LEE;O'DOWD HARDWIN;HENDERSON JAMES A.;KRUEGER ELAINE B.;GRILLOT ANNE-LAURE;LE TIRAN ARNAUD;LIAO YUSHENG;MESSERSMITH DAVID;WANG JIAN;CAO JINGRONG;BANDARAGE UPUL KEERTHI;NANTHAKUMAR SUGANTHINI S. |
| 分类号 |
C07D471/04;C07D401/04;C07D401/14;C07D405/14;C07D409/14;C07D417/14;C07D471/20;C07D491/20 |
主分类号 |
C07D471/04 |
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