| 摘要 |
<p>1,273,241. Heterocyclic amino acids. BRISTOL-MYERS CO. 21 Aug., 1969, No. 41668/69. Headings C2A and C2C. Novel compounds of Formulµ IIa and IIIa and salts thereof are prepared by the removal of protecting groups from intermediates of Formulµ IVa and Va wherein X is a "blocked" primary amino group as used in the field of peptide synthesis and R is a labile ester group, which are prepared by reaction of a compound of Formula VIIa with an ester of Formula CH 3 CO.CO.OR, or its quaternary methiodide, CH 2 =C(X). COOR or CH 3 .CS.CO.OR or by reaction of a compound of formula with a compound of formula HSCH 2 CO.CO.OR or formula The novel compounds are stated to possess antibacterial properties.</p> |
