BIOMARKER FOR VASCULAR ENDOTHELIAL FUNCTION

摘要

A method of determining the vascular endothelial function of a subject using GAPDH as a biomarker is presented, whereby the level of GAPDH mRNA and/or GAPDH protein in a sample obtained from a subject is measured and compared to a reference. A difference in the level of GAPDH mRNA and/or GAPDH protein between that measured for the sample and a reference may be indicative of impaired vascular endothelial function and therefore may indicate the onset of a condition related to impaired vascular endothelial function such as atherosclerosis.