ANTIBODY AND FUNCTIONAL FRAGMENT THEREOF CAPABLE OF TREATING DISEASES ASSOCIATED WITH HEMATOPOIETIC STEM CELL TRANSPLANTATION SUCH AS GRAFT-VERSUS-HOST DISEASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

摘要

[Problem] The objective of the present invention is to provide an antibody and a functional fragment thereof which are capable of treating diseases that are associated with hematopoietic stem cell transplantation such as graft-versus-host disease, and a pharmaceutical composition comprising the same. [Solution] A pharmaceutical composition which comprises an allyl specific anti-HLA antibody or a functional fragment thereof which shows cytotoxicity against cells that express a specific allyl of HLA.