Oxidation resistant bioprosthetic tissues and preparation thereof

摘要

The present invention relates to oxidation resistant bioprosthetic tissues and oxidation resistant bioprosthetic heart valve leaflets. Also provided are methods for preparing the oxidation resistant bioprosthetic tissues and bioprosthetic heart valve leaflets, and methods for preventing oxidative degeneration in bioprosthetic tissues, comprising immobilizing covalently an effective amount of an antioxidant to the bioprosthetic tissue.