| 发明名称 |
INHIBITORS OF PEPTIDYL ARGININE DEIMINASE (PAD) ENZYMES AND USES THEREOF |
| 摘要 |
<p>The present application relates to imidazolidinecliones, compositions comprising these compounds and their use, in particular for the treatment of diseases, disorders or conditions characterized by or associated with the hypercitrullination of proteins by peptidyl arginine deiminase (PAD) enzymes. In particular, the present application includes compounds of Formula I, and compositions and uses thereof: (I).</p> |
| 申请公布号 |
CA2880639(A1) |
申请公布日期 |
2014.02.06 |
| 申请号 |
CA20132880639 |
申请日期 |
2013.08.01 |
| 申请人 |
THE HOSPITAL FOR SICK CHILDREN;UNIVERSITY HEALTH NETWORK |
发明人 |
KOTRA, LAKSHMI;MOSCARELLO, MARIO |
| 分类号 |
C07D403/06;A61K31/4164;A61K31/4178;A61K31/496;A61P25/28;A61P37/06;C07D233/72 |
主分类号 |
C07D403/06 |
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