| 发明名称 |
PURIFICATION OF TRIPHOSPHORYLATED OLIGONUCLEOTIDES USING CAPTURE TAGS |
| 摘要 |
The present invention relates to a method of preparing triphosphate-modified oligonucleotides using a capture tag. The method allows the synthesis and purification of triphosphate-modified oligonucleotides in high yield and purity suitable for pharmaceutical applications. |
| 申请公布号 |
EP2691410(A1) |
申请公布日期 |
2014.02.05 |
| 申请号 |
EP20120710950 |
申请日期 |
2012.03.28 |
| 申请人 |
RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAET BONN |
发明人 |
LUDWIG, JANOS;GOLDECK, MARION;SPROAT, BRIAN |
| 分类号 |
C07H1/04;C07H21/00;C07H21/02 |
主分类号 |
C07H1/04 |
| 代理机构 |
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