PROCESS FOR THE PREPARATION OF N-(2-HYDROXYETHYL)NICOTINAMIDE AND NICORANDIL

摘要

The present invention provides a new preparing method of N-(2-hydroxyethyl) nicotinamide and nicorandil capable of providing an increased yield rate and overcoming a weakness of taking a long time to synthesize N-(2-hydroxyethyl) nicotinamide by preparing the N-(2-hydroxyethyl) nicotinamide without a solvent like the reaction formula 1. [Reference numerals] (AA) N-(2-hydroxyethyl) nicotinamide XRD