发明名称 Excipients for protein stabilization
摘要 This invention is a method of using a class of excipients for protein formulation to reduce and/or eliminate protein aggregation in solutions or solids. This class of compounds contains carbonyl group(s) to form Schiff base(s) with amino groups of proteins and also contains moieties to keep protein molecules spatially separated. This method has never been disclosed anywhere in the literature.
申请公布号 US8642532(B2) 申请公布日期 2014.02.04
申请号 US20080739402 申请日期 2008.11.17
申请人 YANG GUOHAN 发明人 YANG GUOHAN
分类号 A61K38/00;A01N37/10;C07C309/00 主分类号 A61K38/00
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