| 摘要 |
PURPOSE: A novel quinoxaline derivative is provided to differentiate neural progenitor cells or stem cells into nerve cells, and the differentiated neural progenitor cells into specific cells or oligodendrocytes with high efficiency, and to apply the differentiation-induced neural progenitor cells for treating intractable nervous system diseases. CONSTITUTION: A quinoxaline derivative or a salt thereof is denoted by chemical formula 1. A composition for inducing the differentiation of neural progenitor cells or stem cells into nerve cells contains the quinoxaline derivative or the salt thereof as an active ingredient. The stem cells include embryonic stem cells, embryonic germ cells, adult stem cells, and induced pluripotent stem cells. A method for differentiating the neural progenitor cells or the stem cells comprises the step of culturing the neural progenitor cells or the stem cells with the composition. |
