| 发明名称 |
FREMGANGSMÅDE TIL FREMSTILLINGEN AF 18F-MÆRKEDE FOLATER |
| 摘要 |
<p>The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18[F]fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.</p> |
| 申请公布号 |
DK2146944(T3) |
申请公布日期 |
2014.02.03 |
| 申请号 |
DK20080736117T |
申请日期 |
2008.04.11 |
| 申请人 |
MERCK & CIE |
发明人 |
AMETAMEY, SIMON MENSAH;MOSER, RUDOLF;ROSS, TOBIAS LUDWIG;GROEHN, VIOLA;LAM, PHOEBE |
| 分类号 |
C07D475/04;A61B5/00;A61K51/04;C07B59/00 |
主分类号 |
C07D475/04 |
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