TREATING DIABETES WITH DIPEPTIDYL PEPTIDASE-IV INHIBITORS
摘要
The present invention is directed to novel substituted dihydropyrrolopyrazoles of structural Formula I which are inhibitors of the dipeptidyl peptidase-N enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase IV enzyme is involved.
申请公布号
WO2014018355(A1)
申请公布日期
2014.01.30
申请号
WO2013US51001
申请日期
2013.07.18
申请人
MERCK SHARP & DOHME CORP.;BIFTU, TESFAYE;KHAN, TANWEER, A.