发明名称 |
CD147 AS RECEPTOR FOR PILUS-MEDIATED ADHESION OF MENINGOCOCCI TO VASCULAR ENDOTHELIA |
摘要 |
<p>The present invention concerns the use of an inhibitor of an interaction between type IV pilus-associated protein and CD147 for preventing or treating meningoccal bacteraemia and/or infection. The present invention also relates to the combined use of such inhibitor and of an anti-bacterial compound, such as one used to prevent or treat a meningococcal infection. The invention also relates to a method for the prevention and/or treatment of meningococcal bacteraemia and/or infection, and to a method for screening inhibitors of the interaction between type IV pilus-associated protein and CD147.</p> |
申请公布号 |
CA2875391(A1) |
申请公布日期 |
2014.01.30 |
申请号 |
CA20132875391 |
申请日期 |
2013.07.15 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;UNIVERSITE PARIS DESCARTES |
发明人 |
NASSIF, XAVIER;BOURDOULOUS, SANDRINE;JOIN-LAMBERT, OLIVIER |
分类号 |
C07K16/28;A61K39/395 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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