发明名称 |
ADOPTIVE CELL THERAPY WITH YOUNG T CELLS |
摘要 |
The invention provides a method of promoting regression of a cancer in a mammal comprising (i) culturing autologous T cells; (ii) expanding the cultured T cells; (iii) administering to the mammal nonmyeloablative lymphodepleting chemotherapy; and (iv) after administering nonmyeloablative lymphodepleting chemotherapy, administering to the mammal the expanded T cells, wherein the T cells administered to the mammal are about 19 to about 35 days old and have not been screened for specific tumor reactivity, whereupon the regression of the cancer in the mammal is promoted. |
申请公布号 |
US2014030806(A1) |
申请公布日期 |
2014.01.30 |
申请号 |
US201313742541 |
申请日期 |
2013.01.16 |
申请人 |
DEPARTMENT OF HEALTH AND HUMAN SERVICES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY,;HUMAN SERVICES;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND |
发明人 |
DUDLEY MARK E.;ROSENBERG STEVEN A. |
分类号 |
C12N5/0783 |
主分类号 |
C12N5/0783 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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