发明名称 |
INDOLE DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF |
摘要 |
<p>The present invention provides a compound represented by general formula (I), which has an EP1 receptor antagonist activity, or a pharmacologically acceptable salt thereof. The compound (I) of the present invention can be used as a therapeutic agent or prophylactic agent for LUTS, especially for various symptoms of OABs. (In the formula, A represents a pyridine ring or the like; Y1 represents a C1-6 alkylene group or the like; Y2 represents a single bond or the like; R1 represents a hydrogen atom or the like; R2 represents a C1-6 alkyl group; R3 represents a hydrogen atom or the like; R4 represents a hydrogen atom or the like; R5 represents a hydrogen atom, a halogen atom, a C1-6 alkyl group or the like; R6 represents a C1-6 alkyl group, a C3-6 cycloalkyl group or the like; R7 represents a hydrogen atom or the like; X represents a methylene group; and Q represents a single bond or the like.)</p> |
申请公布号 |
WO2014017342(A1) |
申请公布日期 |
2014.01.30 |
申请号 |
WO2013JP69347 |
申请日期 |
2013.07.17 |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD.;KYORIN PHARMACEUTICAL CO., LTD. |
发明人 |
TATANI, KAZUYA;KONDO, ATSUSHI;SETO, SHIGEKI |
分类号 |
C07D209/18;A61K31/404;A61K31/4045;A61K31/4439;A61K31/497;A61K45/00;A61P13/02;A61P43/00;C07D401/06;C07D401/12;C07D403/06;C07D405/06;C07D409/06;C07D413/06;C07D417/06;C07D491/048;C07D491/056;C12N15/09 |
主分类号 |
C07D209/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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