N-CYCLOPROPYL-N-PIPERIDINYL-AMIDE DERIVATIVES AND THEIR USE AS GPR119 MODULATORS

摘要

The present invention relates to compounds of general formula I wherein R1 is selected from a group consisting of -CH2-Ra, wherein Ra denotes C1-6-alkyl optionally mono- or polysubstituted with fluorine, or C3-6- cycloalkyl optionally mono- or polysubstituted with fluorine and optionally substituted with a group selected from among CH3, CF3, and CHF2, and Lp, (Het)Ar1, (Het)Ar2 and n are as defined in the application, which have valuable pharmacological properties, and in particular bind to the GPR119 receptor and modulate its activity.