发明名称 BTK inhibitors
摘要 Provided are 6-5 membered fused pyridine ring compounds according to Formula (I) or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds and their use in therapy. In particular, provided is the use of 6-5 membered fused pyridine ring compounds in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.
申请公布号 AU2012286426(A1) 申请公布日期 2014.01.30
申请号 AU20120286426 申请日期 2012.07.19
申请人 MERCK SHARP & DOHME B.V.;MERCK SHARP & DOHME CORP. 发明人 DE MAN, ADRIANUS P.A.;STERRENBURG, JAN-GERARD;RAAIJMAKERS, HANS C.A.;KAPTEIN, ALLARD;OUBRIE, ARTHUR;REWINKEL, JOHANNES B.M.;JANS, CHRISTIAAN G.J.M.;WIJKMANS, JACOBUS C.H.M.;BARF, TJEERD A.;COOPER, ALAN B.;KIM, RONALD M.;BOGA, SOBHANA BABU;ZHU, HUGH Y.;GAO, XIAOLEI;YAO, XIN;ANAND, RAJAN;WU, HAO;LIU, SHILAN;YANG, CHUNDAO;ALHASSAN, ABDUL-BASIT;WANG, JAMES;YU, YOUNONG;LIU, JIAN;VACCARO, HENRY M.
分类号 C07D497/02;A61K31/437;A61K31/4985;A61K31/519;A61K31/52;A61K31/53;A61P3/10;A61P7/02;A61P9/00;A61P19/02;A61P25/00 主分类号 C07D497/02
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