发明名称 Pyrazolopyrimidine derivatives and pharmaceutical compositions containing the same
摘要 <p>Problem to be Solved To provide a novel compound inhibiting the effect of HSP90, in particular a novel compound inhibiting the function of HSP90 as a chaperone protein and having antitumor activity. Solution The present invention provides a pyrazolopyrimidine compound represented by the formula (1) having various substituents which inhibits the ATPase activity of HSP90 and which has antitumor activity, an HSP90 inhibitor comprising the compound represented by the formula (1), a medicament comprising the compound represented by the formula (1), an anticancer agent comprising the compound represented by the formula (1), a pharmaceutical composition comprising the compound represented by the formula (1) and a method for treating cancer using the compound represented by the formula (1).</p>
申请公布号 IL197513(A) 申请公布日期 2014.01.30
申请号 IL20090197513 申请日期 2009.03.10
申请人 DAIICHI SANKYO COMPANY LIMITED 发明人
分类号 A61K;A61P;C07D 主分类号 A61K
代理机构 代理人
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