发明名称 |
Novel process for the synthesis of 7 -chloro-4 - (piperazin-1-yl)- quinoline |
摘要 |
<p>The present invention provides a new process of synthesis of a polymorph of 7-chloro-4-(piperazin-1-yl)-quinoline of Formula I. Said quinoline compound is substantially pure of any impurities. The present invention further provides the use of the above-mentioned polymorph of 7-chloro-4-(piperazin-1-yl)-quinoline in the synthesis of piperaquine or one of its pharmaceutically acceptable salts.</p> |
申请公布号 |
IL229604(D0) |
申请公布日期 |
2014.01.30 |
申请号 |
IL20130229604 |
申请日期 |
2013.11.25 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
|
分类号 |
C07D |
主分类号 |
C07D |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|