发明名称 |
METHODS AND COMPOUNDS FOR REDUCING THREONYL-TRNA SYNTHETASE ACTIVITY |
摘要 |
<p>The invention includes, in part, methods and compounds for treating diseases and conditions characterized by elevated threonyl-tRNA synthetase (TARS) activity, which include, but are not limited to diseases and conditions in which angiogenesis is elevated as compared to normal. In some embodiments of the invention, a level of a TARS molecule is determined and compared to a control level of TARS to assess a treatment for a disease or condition characterized by elevated TARS activity.</p> |
申请公布号 |
WO2014018620(A1) |
申请公布日期 |
2014.01.30 |
申请号 |
WO2013US51808 |
申请日期 |
2013.07.24 |
申请人 |
UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE |
发明人 |
FRANCKLYN, CHRISTOPHER;LOUNSBURY, KAREN, M.;BOTTEN, JASON |
分类号 |
C12N5/071;A61K39/395;A61P35/00;C07K16/40;C12N5/02 |
主分类号 |
C12N5/071 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|