| 发明名称 |
ARYL-AND HETEROARYL-SUBSTITUTED TETRAHYDROBENZAZEPINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE, AND SEROTONIN |
| 摘要 |
The compounds of the present invention are represented by the following aryl- and heteroaryl-substituted tetrahydrobenzazepine and dihydrobenzazapine derivatives having formulae I(A-E) and formula (II) where the carbon atom designated * is in the R or S configuration, and the substituents X and R-Rare as defined herein. |
| 申请公布号 |
EA019115(B1) |
申请公布日期 |
2014.01.30 |
| 申请号 |
EA20080000341 |
申请日期 |
2006.07.17 |
| 申请人 |
ALBANY MOLECULAR RESEARCH, INC.;BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
MOLINO BRUCE, F.;LIU SHUANG;SAMBANDAM ARUNA;GUZZO PETER, R.;HU MIN;ZHA CONGXIANG;NACRO KASSOUM;MANNING DAVID, D.;ISHERWOOD MATTHEW, L.;FLEMING KRISTEN, N.;CUI WENGE;OLSON RICHARD, E. |
| 分类号 |
A61P25/00;A61K31/55;C07D223/16;C07D403/02;C07D487/02 |
主分类号 |
A61P25/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
