发明名称 |
INTERFERON ALPHA-INDUCED PHARMACODYNAMIC MARKERS |
摘要 |
The present invention encompasses type-I IFN and IFNa-induced PD marker expression profiles, kits, and methods for identifying such IFNa-induced PD marker 5 expression profiles. The type-I IFN and IFNa-induced PD marker expression profiles may also be used in, for example, methods of treating patients having a type-I IFN or IFNa mediated disorder, methods of monitoring disease progression of patients receiving treatment with a therapeutic agent that binds to and modulates IFNa activity, identifying patients as candidates to receive a therapeutic that binds to and neutralizes IFNc activity, and in 10 diagnosing or providing a prognosis to patients having IFNa-induced disorders. C:/poi/word/SPEC-854193[1 ].docx |
申请公布号 |
AU2014200127(A1) |
申请公布日期 |
2014.01.30 |
申请号 |
AU20140200127 |
申请日期 |
2014.01.09 |
申请人 |
MEDIMMUNE, LLC |
发明人 |
YAO, YIHONG;JALLAL, BAHIJA;CIBOTTI, RICARDO;COYLE, ANTHONY;KIENER, PETER |
分类号 |
C07K16/00;A61K39/395;C07K16/24 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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