发明名称 Processes for preparing a substituted gamma-amino acid
摘要 <p>The present invention is related to processes suitable for industrial synthesis of pregabalin from (R)-(−)-3-(carbamoylmethyl)-5-methylhexanoic using sodium hypochlorite as described herein. In addition, the present invention is related to pregabalin which is substantially free of impurities and pharmaceutical compositions comprising pregabalin.</p>
申请公布号 IL205491(A) 申请公布日期 2014.01.30
申请号 IL20100205491 申请日期 2010.05.02
申请人 LABORATORIO CHIMICO INTERNAZIONALE S.P.A.;MEDICHEM S.A. 发明人
分类号 A61K;A61P;C07C 主分类号 A61K
代理机构 代理人
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