| 摘要 |
PROBLEM TO BE SOLVED: To provide a new drug for treating or preventing pain, UI, an ulcer, IBD and IBS.SOLUTION: Provided are a compound represented by the following formula I [where X represents O, S, N-CN, N-OH, or N-OR10, W represents N or C, Rrepresents hydrogen atom, hydroxy group, -OCF3, -halogen atom and the like, Arrepresents a specific 6-membered ring containing a nitrogen atom, Arrepresents a specific heterocycle and the like, each Rindependently represents hydrogen atom, an alkyl group and the like, each Rindependently represents hydrogen atom, an alkyl group and the like] and a pharmaceutical composition containing the compound. Effect of the invention is that the compound is useful for treating or preventing pain, UI, an ulcer, IBD, and IBS by inhibiting a function of Transient Receptor Potential Vanilloid 1 in a cell. |
