发明名称 |
METHOD OF DETECTING AND IDENTIFYING CIRCULATING ANTIGENS IN HUMAN BIOLOGICAL SAMPLES |
摘要 |
Disclosed herein is a method of detecting and identifying antigens that are shed into human bodily fluids during infection. The disclosed method allows circulating antigens associated with a particular infection to be detected within minutes or hours from testing as compared to days required with the current methods. Methods of identifying diagnostic indicators/targets for a given condition or disease are disclosed which include immunizing a veterinary subject with biological fluids obtained from a human infected with particular antigens to identify diagnostic targets for immunoassay. Also disclosed are methods of diagnosing and monitoring a B. pseudomallei-associated condition, such as melioidosis. Point-of-care immunoassays are also provided that can be used to diagnose or monitor the efficacy of a B. pseudomallei-associated condition treatment. These immunoassays can also be used for rapid diagnosis of infection produced by B. pseudomallei, such as meliodosis. |
申请公布号 |
US2014030718(A1) |
申请公布日期 |
2014.01.30 |
申请号 |
US201313804621 |
申请日期 |
2013.03.14 |
申请人 |
ON BEHALF OF THE UNIVERSITY OF NEVADA THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION,;THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF N |
发明人 |
AUCOIN DAVID P.;KOZEL THOMAS R.;SMALLEY CLAIRE |
分类号 |
G01N33/569 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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