| 发明名称 |
Method for Cellular RNA Expression |
| 摘要 |
The present invention relates to enhancing RNA expression in a cell such as a cell transfected with RNA by reducing the activity of RNA-dependent protein kinase (PKR). Thus, the present invention provides methods for expressing RNA in a cell comprising the step of reducing the activity of RNA-dependent protein kinase (PKR) in the cell. Reducing the activity of RNA-dependent protein kinase (PKR) in the cell increases the stability of RNA and/or increases the expression of RNA in the cell. |
| 申请公布号 |
US2014030808(A1) |
申请公布日期 |
2014.01.30 |
| 申请号 |
US201113990729 |
申请日期 |
2011.12.02 |
| 申请人 |
SAHIN UGUR;BEISSERT TIM;POLEGANOV MARCO;HERZ STEPHANIE;BIONTECH AG;UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG- UNIVERSITAT MAINZ;TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITATSMEDIZ- IN DER JGU MAINZ GGMBH (TRON) |
发明人 |
SAHIN UGUR;BEISSERT TIM;POLEGANOV MARCO;HERZ STEPHANIE |
| 分类号 |
C12N15/67;C12N9/12 |
主分类号 |
C12N15/67 |
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