PROCESS FOR CONCENTRATION OF ANTIBODIES AND THERAPEUTIC PRODUCTS THEREOF

摘要

THE PRESENT DISCLOSURE PROVIDES A PROCESS FOR CONCENTRATING PROTEINS INCLUDING AN ULTRAFILTERING, A DIAFILTERING, AND A SECOND ULTRAFILTERING SEQUENCE, AT ELEVATED TEMPERATURES, SUCH AS ABOVE ABOUT 30 °C. THE DISCLOSURE ALSO INCLUDES A PROCESS FOR PREPARING HIGHLY CONCENTRATED ANTIBODY COMPOSITIONS, AND HIGHLY CONCENTRATED ANTIBODY PRODUCTS.