| 发明名称 |
INHIBITION OF AXL SIGNALING IN ANTI-METASTATIC THERAPY |
| 摘要 |
Compositions and methods are provided for alleviating cancer in a mammal by administering a therapeutic dose of a pharmaceutical composition that inhibits activity of AXL protein activity, for example by competitive or non-competitive inhibition of the binding interaction between AXL and its ligand GAS6. |
| 申请公布号 |
ZA201204866(B) |
申请公布日期 |
2014.01.29 |
| 申请号 |
ZA20120004866 |
申请日期 |
2012.06.29 |
| 申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
GIACCIA AMATO J;RANKIN ERINN BRUNO;COCHRAN JENNIFER R;JONES DOUGLAS S;KARIOLIS MIHALIS;FUH KATHERINE;MIAO YU |
| 分类号 |
A61K |
主分类号 |
A61K |
| 代理机构 |
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代理人 |
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