发明名称 |
CYTOLOGICAL METHOD USING THE AUTO FLUORESCENCE OF WHITE CORPUSCLES FOR THE EARLY DIAGNOSIS AND THE MONITORING OF INFECTIONS |
摘要 |
The present invention relates to an in vitro method for diagnosing the infectious state of an individual on the basis of a sample of white corpuscles arising from a biological specimen taken from an organ potentially infected by a pathogenic micro-organism of said individual, comprising at least the following two steps: i) measuring the mean cellular intensity of the autofluorescence of said sample, and ii) comparing the intensity measured in step i) with a control value, so as to determine the infectious state of said individual. The diagnostic method of the invention uses a routine optical material making it possible to work in wavelength regions which are compatible with the cellular autofluorescence, and thus constitutes a rapid, reliable and inexpensive aid for the diagnosis or monitoring of an infection in an individual. |
申请公布号 |
EP2689236(A1) |
申请公布日期 |
2014.01.29 |
申请号 |
EP20120711151 |
申请日期 |
2012.03.22 |
申请人 |
UNIVERSITE DE NANTES;UNIVERSITE PARIS-SUD 11;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);CHU NANTES |
发明人 |
ASEHNOUNE, KARIM;FONTAINE-AUPART, MARIE-PIERRE;LECART, SANDRINE;MONSEL, ANTOINE;ROQUILLY, ANTOINE |
分类号 |
G01N21/64 |
主分类号 |
G01N21/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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