发明名称 Catalyst for cross-coupling reaction comprising unsubstituted or substituted bisphosphinobenzenes
摘要 The present invention provides a process for efficiently producing an alkylated aromatic compound in good yield, by a cross-coupling reaction between an alkyl halide and an aromatic magnesium reagent. A process for producing an aromatic compound represented by Formula (1): R-Ar'(1) wherein R is a hydrocarbon group, and Ar' is an aryl group; the process comprising: reacting a compound represented by Formula (2): R-X(2) wherein X is a halogen atom, and R is as defined above, with a magnesium reagent represented by Formula (3): Ar'-MgY(3) wherein Y is a halogen atom, and Ar' is as defined above, in the presence of a catalyst for cross-coupling reactions comprising an iron compound and a bisphosphine compound represented by Formula (4): wherein Q is a divalent group derived from an aromatic ring by removing two hydrogen (H) atoms on adjacent carbon atoms; and each Ar is independently an aryl group.
申请公布号 US8637710(B2) 申请公布日期 2014.01.28
申请号 US20090737288 申请日期 2009.03.10
申请人 NAKAMURA MASAHARU;HATAKEYAMA TAKUJI;FUJIWARA YU-ICHI;KYOTO UNIVERSITY 发明人 NAKAMURA MASAHARU;HATAKEYAMA TAKUJI;FUJIWARA YU-ICHI
分类号 G07F9/02 主分类号 G07F9/02
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