发明名称 |
Methods of detecting target nucleic acids |
摘要 |
The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore. |
申请公布号 |
US8637247(B2) |
申请公布日期 |
2014.01.28 |
申请号 |
US201213590794 |
申请日期 |
2012.08.21 |
申请人 |
SHARAF MUHAMMAD;WOUDENBERG TIMOTHY;MULLAH KHAIRUZZAMAN BASHAR;APPLIED BIOSYSTEMS, LLC |
发明人 |
SHARAF MUHAMMAD;WOUDENBERG TIMOTHY;MULLAH KHAIRUZZAMAN BASHAR |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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