发明名称 Identification of a JAK2 mutation in polycythemia vera
摘要 The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative disorders, or to the detection of the JAK2 V617F variant in myeloproliferative disorders allowing their reclassification in a new nosological group.
申请公布号 US8637235(B2) 申请公布日期 2014.01.28
申请号 US20080234616 申请日期 2008.09.19
申请人 VAINCHENKER WILLIAM;UGO VALERIE;JAMES CHLOE;LE COUEDIC JEAN-PIERRE;CASADEVALL NICOLE;INSTITUT GUSTAVE-ROUSSY;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE SCIENTIFIQUE (CNRS);ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS;UNIVERSITE DE VERSAILLES-ST QUENTIN EN YVELINES;UNIVERSITE PARIS-SUD 发明人 VAINCHENKER WILLIAM;UGO VALERIE;JAMES CHLOE;LE COUEDIC JEAN-PIERRE;CASADEVALL NICOLE
分类号 C12Q1/68;C07H21/04;C12P19/34 主分类号 C12Q1/68
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