发明名称 |
Identification of a JAK2 mutation in polycythemia vera |
摘要 |
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative disorders, or to the detection of the JAK2 V617F variant in myeloproliferative disorders allowing their reclassification in a new nosological group. |
申请公布号 |
US8637235(B2) |
申请公布日期 |
2014.01.28 |
申请号 |
US20080234616 |
申请日期 |
2008.09.19 |
申请人 |
VAINCHENKER WILLIAM;UGO VALERIE;JAMES CHLOE;LE COUEDIC JEAN-PIERRE;CASADEVALL NICOLE;INSTITUT GUSTAVE-ROUSSY;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE SCIENTIFIQUE (CNRS);ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS;UNIVERSITE DE VERSAILLES-ST QUENTIN EN YVELINES;UNIVERSITE PARIS-SUD |
发明人 |
VAINCHENKER WILLIAM;UGO VALERIE;JAMES CHLOE;LE COUEDIC JEAN-PIERRE;CASADEVALL NICOLE |
分类号 |
C12Q1/68;C07H21/04;C12P19/34 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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