PROCESS FOR THE PREPARATION OF AN INTERMEDIATE USEFUL IN PRODUCTION OF AZOXYSTROBIN

摘要

The invention provides a process for preparing a compound of formula (IV) (see formula IV) where W is the methyl (E)-2-(3-methoxy)acrylate group C(CO2CH3)=CHOCH3, which comprises the steps of: (i) reacting the compound of formula (IV) where W is the methyl 2-(3,3- dimethoxy)-propanoate group CH(CO2CH3)CH(OCH3)2 with a reagent that will protect the hydroxyl group of the compound of formula (IV) from reaction during subsequent demethanolysis; (ii) eliminating methanol from the hydroxyl-protected compound formed in step (i); and (iii) removing the hydroxyl-protecting group formed in step (i) to form the compound of formula (IV) where W is the methyl (E)-2-(3-methoxy)acrylate group.