| 摘要 |
The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, (see formula I) wherein X1, C1, and D1 are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting Plk1, Plk1 causes mitotic arrest, and inhibitors of Plk1 are cytotoxic agents that are useful for treatment of diseases of cellular proliferation, such as, for example, cancer. |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
DIEBOLD, ROBERT B.;DJURIC, STEVAN W.;GIRANDA, VINCENT L;HEXAMER, LAURA;LIN, NAN-HORNG;MIYASHIRO, JULIE M.;PENNING, THOMAS D.;PRZYTULINSKA, MAGDALENA;SOWIN, THOMAS;SULLIVAN, GERARD;TAO, ZHI-FU;TONG, YUNSONG;VASUDEVAN, ANIL;WANG, LE;WOODS, KEITH W.;XIA, ZHIREN;ZHANG, HENRY Q. |
