| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to novel analogues of 11,15,19-trihydroxy-9-halo-prostaglandin and their application as eye hypotensive medications, medications for treatment of glaucoma, as well as for improvement of hair growth or improvement of hair outlook, namely to compounds of formula, where dash and dash line stands for presence or absence of bond; Y has from 1 to 14 carbon atoms and is functional group of carboxylic acid or its ester; X represents halogen; Z represents -OH; each of Ris independently CH, or, if Rforms double bond with other R, both are CH, and each R is independently -H.EFFECT: increased efficiency of compound application.11 cl, 2 tbl, 2 dwg |
