METHOD OF OBTAINING ANESTHESINUM

摘要

FIELD: chemistry.SUBSTANCE: invention related to method of obtaining ethyl ether of n-aminobenzoic acid (anesthesinum) of formula, which possesses local anesthetic action and is semi-product in Novocain synthesis. Method lies in reduction of ethyl ether of n-nitrobenzoic acid with further separation of target product. Method is characterised by the following: to simplify technology and increase product quality reduction process is carried out with mixing in isopropyl alcohol in presence of Raney Ni catalyst under hydrogen pressure 2.0-4.0 atm and temperature 60-70°C.EFFECT: method makes it possible to avoid formation of considerable quantities of by-products and obtain anesthesinum with high output.1 ex