CELL PERMEABLE SIRT2 FUSION PROTEIN

摘要

Refined SIRT2 fusion protein is penetrated into a Raw 264.7 cell in a time and injection amount dependent way, and protects the cell from cell death and cytotoxicity induced by lipopolysaccharide and hydrogen peroxide. The penetrated SIRT2 fusion protein also controls the activation of NF-kB and MAPKs (mitogen-activated protein kinases), and the expression of cytokine.